Information
Our products are formulated using over 60 years of research by world renowned scientists based in the Czech Republic.
In 1955 Prof. Jan Kabelik laid the basics of the scientific research into the healing effects of cannabis, pioneering a legacy of research in the Czech Republic that continues to this day. His colleagues Prof. Zdeněk Krejčí and chemist František Šantavy were the first to discover and isolate cannabidiol acid or CBD in its molecular form. In 1963 Professor Šantavý published the correct absolute configuration of CBD and THC, four years ahead of Profs Raphael Mechoulam and Gaoni in Israel who independently determined and verified the findings. Many of these ground-breaking papers were published behind the Iron Curtain in the Czech language*. If they had been published in English, scientific journals of their work would now be cited all over the world.
Today this inherited knowledge lays the foundation upon which our world leading formulations are created. Our Czech formulators are scientists that not only have access to decades of cannabinoid research but also the world-class expertise in formulation processes and combining bioactive ingredients to deliver the most effective CBD products.
*Research papers have been translated into English and are not the sole IP of HIR.
White Paper 01Published 8 Nov 2021
The Importance of Interplay Between the Endo Cannabinoid System CBD in Skincare
As part of HIR’s key objective to explore the effects and benefits of Cannabidiol (CBD), HIR present this first white paper that explores the importance of interplay between the Endo-Cannabi- noid System(ECS) and CBD in skincare.
View (PDF) →
White Paper 02Published 13 Dec 2021
The Topical Application of Cannabidiol for Pain Relief
As part of HIR’s ongoing efforts to evaluate the effects and benefits of Cannabidiol (CBD), HIR present their second white paper that explores how the topical application of CBD significantly contributes to pain relief.
View (PDF) →
White Paper 03Published 5 Apr 2022
The Topical Application of CBD and Anti Aging
This paper is the third white paper to be published by Healthcare International Research and discusses how the topical application of Cannabidiol (CBD) can contribute to anti-aging.
View (PDF) →
White Paper 04Published 11 May 2022
The Importance of Interplay between the Endocannabinoid System and Cannabidiol in Pain Relief
This white paper was completed for HIR by Harry Rule. Harry is a leading independent researcher specialising in qualitative research across a wide range of sectors.
View (PDF) →
White Paper 05Published 15 Jun 2022
The Antioxidative Properties of Cannabidiol
This white paper was completed for HIR by Harry Rule. Harry is a leading independent researcher specialising in qualitative research across a wide range of sectors.
View (PDF) →
White Paper 06Published 3 Oct 2022
The Anti Inflammatory Properties of Cannabidiol
This is the sixth white paper published by Healthcare International Research.
View (PDF) →
White Paper 07Published 11 Nov 2024
HEMPE User Research v Clinical Literature
View (PDF) →
*Research papers have been translated into English and are not the sole IP of HIR.
Overview of Findings from the Palackian University of OlomoucPublished 2 Mar 1955
Monograph of Prof Jan Kabeliks Team on the Study of the Effects of Cannabis
In the fifties, Prof. Jan Kabelík and his colleagues from his research institute in Velké Losiny found remarkably effective bactericidal and anesthetic substances in cannabis during a systematic survey of plant antibiotics.
View (PDF) →
Paper 1Published 2 Mar 1955
Introduction of the study Cannabis as a Medicine
Introductory text by prof. Kabelík to the monograph, explaining the history of its origin and the reasons for studying this plant.
View (PDF) →
Paper 2Published 2 Mar 1955
Historical Overview of the Therapeutic Effect of Cannabis
An overview of indications of cannabis - hemp tops and seeds - from old herbaria, folk medicine and today's official medicine is given, if the remnants of the use of Extr. cannabis.
View (PDF) →
Paper 3Published 2 Mar 1955
Antibacterial Effect of Substances From Cannabis Indica L
In the Institute of Hygienic Medicine of the Faculty of Medicine of Palacký University in Olomouc, a systematic survey of the flora of our climate zone was carried out for the content of substances with antibacterial effects.
View (PDF) →
Paper 4Published 2 Mar 1955
Isolation of Other Substances from the Leaves of Indian Cannabis Sativa L
It has been found that the antibacterial substances of cannabis leaves (Cannabis sativa L., indica variety) have an acidic character. Based on this, an acid was isolated in the form of its acetyl derivative, which has retained antibacterial properties against some bacterial strains.
View (PDF) →
Paper 5Published 2 Mar 1955
Pharmacodynamic Effect of Cannabis Indica Substances
Evaluation of the pharmacological effect of substances present in Cannabis indica. During the analysis of the substances contained in Cannabis indica, several distinct effects were found. These are analgesic, anticonvulsant and locally anaesthetic effects.
View (PDF) →
Paper 6Published 2 Mar 1955
Therapeutical Results of Application of Substances from Cannabis Ind in Dentistry
The application of active substances from Cannabis indica shows a clear therapeutic effect in the treatment of herpes labialis, periodontal painful pockets, gingival hoods above wisdom teeth, dry socket, canker sores and ulcerative gingivostomatitis.
View (PDF) →
Paper 7Published 2 Mar 1955
Use of Cannabis Indica Extract in Conservative Dentistry
Furthermore, substances from Cannabis indica mixed with sterile dentin powder were used for treatment aimed at preserving vital dental pulp. The anesthetic effect of extr. Cannabis, in many unsuccessfully treated cases there was a painlessness for many days, in many even painless necrosis.
View (PDF) →
Paper 8Published 2 Mar 1955
Effect of Cannabis Indica Substances in Otorhinolaryngology
Excellent effect of antibiotics from cannabis has been found in acute otitis, furuncles of the entrance to the nose and external auditory canal. In chronic otitis, it has proven itself in most cases, fails in pyocyanea and proteum infections.
View (PDF) →
Paper 9Published 2 Mar 1955
Cannabis Indica in the Treatment of Chronic Otitis Media
In a short-term study lasting 3 weeks, Cannabis indica was tested in 18 patients with chronic otitis media and in 4 patients in the wound after anthropomy. In 13 cases of chronic otitis, there was a substantial improvement.
View (PDF) →
Paper 10Published 2 Mar 1955
Topical Effect of Cannabis Indica in the Treatment of Specific Fistulas
Except in cases of pyocyaneal infection, cannabis extract has a beneficial healing effect in chronic specific fistulas.
View (PDF) →
Paper 11Published 2 Aug 1955
The Importance of Hemp Seed in Tuberculosis Therapy
The use of hemp seed in the treatment of tuberculosis is based on thirty years of experience gained in the field of medical nutrition. Hemp seed ground and extracted with milk at a temperature between 60 and 80 ° C has a significant therapeutic effect even in small doses.
View (PDF) →
Paper 12Published 2 Aug 1955
Summary of the study Cannabis as a Medicine
Summary of the results of the entire study.
View (PDF) →
Paper 13Published 2 Aug 1955
Discussion on Papers
Discussion on individual papers on the topic of cannabis presented at the conference.
View (PDF) →
Paper 14Published 10 Dec 1954
Hemp As A Medicant
The cycle of lectures and discussions "Hemp as a Medicine" was originally created for a scientific conference of universities held in Olomouc on December 10, 1954. One section was dedicated to medicinal and especially to the antibiotic effects of hemp.
View (PDF) →
Topical cannabidiol is well tolerated in individuals with a history of elite physical performance and chronic lower extremity pain
Cannabidiol in sports: insights on how CBD could improve performance and recovery
Cannabidiol use and effectiveness: real-world evidence from a Canadian medical cannabis clinic
Jan Kabelík, the first professor of microbiology in the Czech lands, was born 130 years ago
Natural antibiotic. Jan Kabelík discovered the effects of cannabis
Effectiveness of Cannabidiol to Manage Chronic Pain: A Systematic Review
Cannabidiol in Rheumatic Diseases
Topical Cannabidiol is Well Tolerated in Individuals with Chronic Lower Extremity Pain
Use of Cannabidiol (CBD) for the Treatment of Chronic Pain
A Balanced Approach for Cannabidiol Use in Chronic Pain
The Role of Cannabidiol (CBD) in Chronic Pain Management: An Overview
Medical Cannabis or Cannabinoids for Chronic Pain: A Systematic Review and Meta-Analysis
6 Benefits and Uses of CBD Oil (Plus Side Effects) - Cannabidiol, or CBD, is a chemical compound in cannabis with a variety of uses. Here are 6 benefits of CBD oil. (healthline.com)
Cannabidiol (CBD): What we know and what we don't - Harvard Health - Cannabidiol (CBD) is an active ingredient in cannabis that is derived from the hemp plant, but it does not cause a high and is not addictive. CBD has been shown to be effective in treating conditions like pain, insomnia, and anxiety. (health.harvard.edu)
Medical cannabis (cannabis oil) - NHS - Information from the NHS website on medical cannabis. (nhs.uk)
What Are the Benefits of CBD? - The New York Times - More than 60 percent of CBD users were taking it for anxiety, according to a survey of 5,000 people. Does it help? (nytimes.com)
CBD Oil: 9 Science-Backed Benefits - CBD oil has skyrocketed in popularity thanks to its purported calming effects. Here are nine ways studies suggest CBD oil could benefit your health. (forbes.com)
CBD oil for pain management: Effects, benefits, and uses - Cannabidiol or CBD oil has become popular for pain treatment. This article looks at how it works, how to use it, and the benefits and risks of CBD oil. (medicalnewstoday.com)
CBD: Health Benefits, Risks, Dosage, and More - Find out the benefits of CBD, what it is, and the associated risks. (webmd.com)
CBD for Arthritis Pain | Arthritis Foundation - People with arthritis may consider CBD products for pain relief. Learn what science and experts say about CBD's benefits, risks, different ways the product can be used and how to be a smart shopper. (arthritis.org)
CBD oil and cancer: 9 things to know - Wondering whether you should use CBD oil to cope with cancer treatment and its side effects? We spoke with Kimberson Tanco, M.D., to separate fact from fiction. (mdanderson.org)
CBD Oil for Dogs: What Is It and What Does It Do?(akc.org)
CBD: Safe and effective? - Mayo Clinic - Interested in using CBD? Here's what you need to know about the risks and benefits of using this drug. (mayoclinic.org)
CBD: What is it, and can it help the heart? | BHF - In recent years, CBD oil has been called the 'miracle of the modern age'. But what is CBD, and can CBD products help the heart? (bhf.org.uk)
Cannabis, CBD oil and cancer| Cancer Research UK - Cannabis is a plant and a class B drug. CBD oil is a chemical found in cannabis. Research is looking at the substances in cannabis to see if it might help treat cancer. (cancerresearchuk.org)
CBD: What Is It, What Does It Do, and What Are the Benefits? | Lifespan - CBD is a commonly used product, can be found in many items such as oils and food and is reported to have numerous health benefits. (lifespan.org)
What You Need to Know (And What We're Working to Find Out) About Products Containing Cannabis or Cannabis-derived Compounds, Including CBD | FDA - The FDA is working to answer questions about the science, safety, and quality of products containing cannabis and cannabis-derived compounds, particularly CBD. (fda.gov)
CBD Oil Benefits vs. Side Effects: Is It Safe? - CBD oil is made from hemp plants. It may help treat pain, anxiety, and seizures. Here is what you should know before trying it. (verywellhealth.com)
CBD (cannabidiol): What does it do and how does it affect the brain & body? - Learn the science behind cannabidiol (CBD) and the brain, and find out how it's able to provide such a broad range of potential medical benefits. (leafly.com)
Cannabidiol in Anxiety and Sleep: A Large Case Series - PMC - Cannabidiol (CBD) is one of many cannabinoid compounds found in cannabis. It does not appear to alter consciousness or trigger a “high.” A recent surge in scientific publications has found preclinical and clinical evidence documenting ... (ncbi.nlm.nih.gov)
Is CBD Safe for People With Cancer? | Cancer.Net - Cannabidiol (CBD) has become a buzzword within the cancer community. But while some people with cancer have found CBD to be helpful in managing side effects, research does not yet support CBD's use for cancer treatment. Here, find out what CBD is, ho (cancer.net)
The Impact of Cannabidiol on Human Brain Function: A Systematic Review - PubMed - Background: Accumulating evidence suggests that the non-intoxicating cannabinoid compound cannabidiol (CBD) may have antipsychotic and anxiolytic properties, and thus may be a promising new agent in the treatment of psychotic and anxiety (pubmed.ncbi.nlm.nih.gov